Molecular Neurodegeneration

official impact factor 5.36

Open Access Research article

Dynamic transport and localization of alpha-synuclein in primary hippocampal neurons

Mong-Lin Yang1, Linda Hasadsri1,2, Wendy S Woods3 and Julia M George3*

Author Affiliations

1 Department of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA

2 Medical Scholars Program, University of Illinois at Urbana-Champaign, Urbana, IL, USA

3 Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Urbana, IL, USA

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Molecular Neurodegeneration 2010, 5:9 doi:10.1186/1750-1326-5-9

Published: 9 February 2010

Additional files

Additional file 1:

Bidirectional movement of ASGFP particles. Cultured rat hippocampal neurons were transfected with ASGFP at 7DIV, with live images acquired at 10 DIV. Arrows (appearing at 32s and 40s, respectively) indicate distinct particles traveling in opposite directions. The time stamp at the top right is shown in min:sec:ms and scale bar = 100 μm. The image series is acquired at 1.7s/frame and played back at 0.2s/frame.

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