Molecular Neurodegeneration

Editors-in-Chief

Guojun Bu, Mayo Clinic
Huaxi Xu, Sanford-Burnham Medical Research Institute

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Research article

Nurr1 regulates Top IIbeta and functions in axon genesis of mesencephalic dopaminergic neurons

Heng X, Jin G, Zhang X, Yang D, Zhu M, Fu S, Li X and Le W Molecular Neurodegeneration 2012, 7:4 (2 February 2012)
Research article

Both common variations and rare non-synonymous substitutions and small insertion/deletions in CLU are associated with increased Alzheimer risk

Bettens K, Brouwers N, Engelborghs S, Lambert JC, Rogaeva E, Vandenberghe R, Le Bastard N, Pasquier F et al. Molecular Neurodegeneration 2012, 7:3 (16 January 2012)
Research article

Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway

Tong Y, Giaime E, Yamaguchi H, Ichimura T, Liu Y, Si H, Cai H, Bonventre JV et al. Molecular Neurodegeneration 2012, 7:2 (9 January 2012)
Research article

Adeno-Associated Virus-Mediated Brain Delivery of 5-Lipoxygenase modulates the AD-like phenotype of APP mice

Chu J, Giannopoulos PF, Ceballos-Diaz C, Golde TE and Pratico D Molecular Neurodegeneration 2012, 7:1 (5 January 2012)
Research article

The Alzheimer's β-secretase enzyme BACE1 is required for accurate axon guidance of olfactory sensory neurons and normal glomerulus formation in the olfactory bulb

Rajapaksha TW, Eimer WA, Bozza TC and Vassar R Molecular Neurodegeneration 2011, 6:88 (28 December 2011)
Research article

Transgenic neuronal overexpression reveals that stringently regulated p23 expression is critical for coordinated movement in mice

Gong P, Roseman J, Fernandez CG, Vetrivel KS, Bindokas VP, Zitzow LA, Kar S, Parent AT et al. Molecular Neurodegeneration 2011, 6:87 (28 December 2011)
Research article

Resorufin analogs preferentially bind cerebrovascular amyloid: potential use as imaging ligands for cerebral amyloid angiopathy

Han BH, Zhou M, Vellimana AK, Milner E, Kim DH, Greenberg JK, Chu W, Mach RH et al. Molecular Neurodegeneration 2011, 6:86 (22 December 2011)
Review

Adult hippocampal neurogenesis and its role in Alzheimer's disease

Mu Y and Gage FH Molecular Neurodegeneration 2011, 6:85 (22 December 2011)
Research article

Microglial p38alpha MAPK is critical for LPS-induced neuron degeneration through a mechanism involving TNFalpha

Xing B, Bachstetter AD and Van Eldik LJ Molecular Neurodegeneration 2011, 6:84 (20 December 2011)
Research article

Analysis of striatal transcriptome in mice overexpressing human wild-type alpha-synuclein supports synaptic dysfunction and suggests mechanisms of neuroprotection for striatal neurons

Cabeza-Arvelaiz Y, Fleming SM, Richter F, Masliah E, Chesselet MF and Schiestl RH Molecular Neurodegeneration 2011, 6:83 (13 December 2011)
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Comments

Correction of one word

Comment on: Tapia-González et al. Molecular Neurodegeneration 2012, 6:72
Magnification comment addition to Figure 1

Comment on: Olabarria et al. Molecular Neurodegeneration 2011, 6:55
Acknowledgments

Comment on: Altmeppen et al. Molecular Neurodegeneration 2011, 6:36

ALS-associated SOD1 mutations adopt misfolded conformations

New insights into the biology and pathophysiology of amyloid precursor protein and link to AD

Expression of mutant TDP-43 induces neuronal dysfunction in transgenic mice

Parkinson's update: Smad3 deficiency may induce a-synuclein aggregation

Aims & scope

Molecular Neurodegeneration is an open access, peer-reviewed online journal that encompasses all aspects of neurodegeneration research at the molecular and cellular levels.

Society information

Molecular Neurodegeneration is the official journal of the American Health Assistance Foundation.

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Molecular Neurodegeneration on Twitter

Twitter updates

Study identifies a new genetic risk association of #Alzheimer's disease with rare coding CLU variations http://t.co/ZzZzxwX0 1:20 PM Jan 19th, 2012
#Parkinson's update: Leucine-rich repeat kinase 2 important for the dynamic regulation of autophagy function in vivo. http://t.co/AsraHBmT 1:15 PM Jan 18th, 2012
Adeno-Associated Virus-Mediated Brain Delivery of 5-Lipoxygenase modulates the AD-like phenotype of APP mice http://t.co/FKT2QyR5 2:15 PM Jan 17th, 2012

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ISSN: 1750-1326