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1:
Zerbinatti CV, Cordy JM, Chen CD, Guillily M, Suon S, Ray WJ, Seabrook GR, Abraham CR, Wolozin B.
Free in PMC
Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein.
Mol Neurodegener. 2008 Mar 18;3:5.
PMID: 18348724 [PubMed - in process]
2:
Koldamova RP, Lefterov IM, Staufenbiel M, Wolfe D, Huang S, Glorioso JC, Walter M, Roth MG, Lazo JS.
Free Full Text
The liver X receptor ligand T0901317 decreases amyloid beta production in vitro and in a mouse model of Alzheimer's disease.
J Biol Chem. 2005 Feb 11;280(6):4079-88. Epub 2004 Nov 22.
PMID: 15557325 [PubMed - indexed for MEDLINE]
3:
Pastorino L, Sun A, Lu PJ, Zhou XZ, Balastik M, Finn G, Wulf G, Lim J, Li SH, Li X, Xia W, Nicholson LK, Lu KP.
Abstract
The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production.
Nature. 2006 Mar 23;440(7083):528-34. Erratum in: Nature. 2007 Mar 15;446(7133):342.
PMID: 16554819 [PubMed - indexed for MEDLINE]
4:
Dorval V, Mazzella MJ, Mathews PM, Hay RT, Fraser PE.
Free in PMC
Modulation of Abeta generation by small ubiquitin-like modifiers does not require conjugation to target proteins.
Biochem J. 2007 Jun 1;404(2):309-16.
PMID: 17346237 [PubMed - indexed for MEDLINE]
5:
Sambamurti K, Greig NH, Lahiri DK.
Abstract
Advances in the cellular and molecular biology of the beta-amyloid protein in Alzheimer's disease.
Neuromolecular Med. 2002;1(1):1-31. Review.
PMID: 12025813 [PubMed - indexed for MEDLINE]
6:
Petanceska SS, Gandy S.
Abstract
The phosphatidylinositol 3-kinase inhibitor wortmannin alters the metabolism of the Alzheimer's amyloid precursor protein.
J Neurochem. 1999 Dec;73(6):2316-20.
PMID: 10582589 [PubMed - indexed for MEDLINE]
7:
Tansley GH, Burgess BL, Bryan MT, Su Y, Hirsch-Reinshagen V, Pearce J, Chan JY, Wilkinson A, Evans J, Naus KE, McIsaac S, Bromley K, Song W, Yang HC, Wang N, DeMattos RB, Wellington CL.
Free Full Text
The cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of beta-amyloid precursor protein.
J Lipid Res. 2007 May;48(5):1022-34. Epub 2007 Feb 10.
PMID: 17293612 [PubMed - indexed for MEDLINE]
8:
Rossner S, Ueberham U, Schliebs R, Perez-Polo JR, Bigl V.
Abstract
The regulation of amyloid precursor protein metabolism by cholinergic mechanisms and neurotrophin receptor signaling.
Prog Neurobiol. 1998 Dec;56(5):541-69. Review.
PMID: 9775403 [PubMed - indexed for MEDLINE]
9:
Xia W, Zhang J, Ostaszewski BL, Kimberly WT, Seubert P, Koo EH, Shen J, Selkoe DJ.
Abstract
Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.
Biochemistry. 1998 Nov 24;37(47):16465-71.
PMID: 9843412 [PubMed - indexed for MEDLINE]
10:
Turner PR, O'Connor K, Tate WP, Abraham WC.
Abstract
Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory.
Prog Neurobiol. 2003 May;70(1):1-32. Review.
PMID: 12927332 [PubMed - indexed for MEDLINE]
11:
Nelson TJ, Alkon DL.
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Oxidation of cholesterol by amyloid precursor protein and beta-amyloid peptide.
J Biol Chem. 2005 Feb 25;280(8):7377-87. Epub 2004 Dec 8.
PMID: 15591071 [PubMed - indexed for MEDLINE]
12:
Hoe HS, Cooper MJ, Burns MP, Lewis PA, van der Brug M, Chakraborty G, Cartagena CM, Pak DT, Cookson MR, Rebeck GW.
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The metalloprotease inhibitor TIMP-3 regulates amyloid precursor protein and apolipoprotein E receptor proteolysis.
J Neurosci. 2007 Oct 3;27(40):10895-905.
PMID: 17913923 [PubMed - indexed for MEDLINE]
13:
Xu Y, Liu Y, Ridgway ND, McMaster CR.
Free Full Text
Novel members of the human oxysterol-binding protein family bind phospholipids and regulate vesicle transport.
J Biol Chem. 2001 May 25;276(21):18407-14. Epub 2001 Feb 26.
PMID: 11279184 [PubMed - indexed for MEDLINE]
14:
Vaya J, Schipper HM.
Abstract
Oxysterols, cholesterol homeostasis, and Alzheimer disease.
J Neurochem. 2007 Sep;102(6):1727-37. Epub 2007 Jun 15. Review.
PMID: 17573819 [PubMed - indexed for MEDLINE]
15:
Nunan J, Williamson NA, Hill AF, Sernee MF, Masters CL, Small DH.
Abstract
Proteasome-mediated degradation of the C-terminus of the Alzheimer's disease beta-amyloid protein precursor: effect of C-terminal truncation on production of beta-amyloid protein.
J Neurosci Res. 2003 Nov 1;74(3):378-85.
PMID: 14598314 [PubMed - indexed for MEDLINE]
16:
Brown J 3rd, Theisler C, Silberman S, Magnuson D, Gottardi-Littell N, Lee JM, Yager D, Crowley J, Sambamurti K, Rahman MM, Reiss AB, Eckman CB, Wolozin B.
Free Full Text
Differential expression of cholesterol hydroxylases in Alzheimer's disease.
J Biol Chem. 2004 Aug 13;279(33):34674-81. Epub 2004 May 17.
PMID: 15148325 [PubMed - indexed for MEDLINE]
17:
Greenfield JP, Gross RS, Gouras GK, Xu H.
Abstract
Cellular and molecular basis of beta-amyloid precursor protein metabolism.
Front Biosci. 2000 Jan 1;5:D72-83. Review.
PMID: 10702374 [PubMed - indexed for MEDLINE]
18:
Xie Z, Dong Y, Maeda U, Xia W, Tanzi RE.
Free Full Text
RNA interference silencing of the adaptor molecules ShcC and Fe65 differentially affect amyloid precursor protein processing and Abeta generation.
J Biol Chem. 2007 Feb 16;282(7):4318-25. Epub 2006 Dec 14.
PMID: 17170108 [PubMed - indexed for MEDLINE]
19:
Gandy S, Petanceska S.
Abstract
Regulation of Alzheimer beta-amyloid precursor trafficking and metabolism.
Biochim Biophys Acta. 2000 Jul 26;1502(1):44-52. Review.
PMID: 10899430 [PubMed - indexed for MEDLINE]
20:
Offe K, Dodson SE, Shoemaker JT, Fritz JJ, Gearing M, Levey AI, Lah JJ.
Free Full Text
The lipoprotein receptor LR11 regulates amyloid beta production and amyloid precursor protein traffic in endosomal compartments.
J Neurosci. 2006 Feb 1;26(5):1596-603.
PMID: 16452683 [PubMed - indexed for MEDLINE]
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