Presenilins are required for maintenance of neural stem cells in the developing brain.

Reduced beta-amyloid production and increased inflammatory responses in presenilin conditional knock-out mice.

Pax6 is required to regulate the cell cycle and the rate of progression from symmetrical to asymmetrical division in mammalian cortical progenitors.

Mice lacking both presenilin genes exhibit early embryonic patterning defects.

Impaired cell cycle control of neuronal precursor cells in the neocortical primordium of presenilin-1-deficient mice.

Identification of self-replicating multipotent progenitors in the embryonic nervous system by high Notch activity and Hes5 expression.

Cell cycle progression is required for nuclear migration of neural progenitor cells.

Role of presenilin-1 in murine neural development.

Presenilin-1 regulates neuronal differentiation during neurogenesis.

Insulin-like growth factor-I accelerates the cell cycle by decreasing G1 phase length and increases cell cycle reentry in the embryonic cerebral cortex.

Presenilin-1 is expressed in neural progenitor cells in the hippocampus of adult mice.

Selection of differentiating cells by different levels of delta-like 1 among neural precursor cells in the developing mouse telencephalon.

Analysis of ERK2 Function in Neural Stem/Progenitor Cells Via Nervous System-Specific Gene Disruption.

Roles of the basic helix-loop-helix genes Hes1 and Hes5 in expansion of neural stem cells of the developing brain.

Ubiquitin C-terminal hydrolase L1 regulates the morphology of neural progenitor cells and modulates their differentiation.

Treatment with deferoxamine increases neurons from neural stem/progenitor cells.

Non-cell-autonomous action of STAT3 in maintenance of neural precursor cells in the mouse neocortex.

Role of presenilin-1 in cortical lamination and survival of Cajal-Retzius neurons.

Neural progenitor cells do not differentiate prematurely in presenilin-1 null mutant mice.