Your browser version may not work well with NCBI's Web applications. More information here...

Recent Activity

Items 1 - 20 of 99
of 5Next
1:
Rebeck GW, LaDu MJ, Estus S, Bu G, Weeber EJ.
Free in PMC
The generation and function of soluble apoE receptors in the CNS.
Mol Neurodegener. 2006 Oct 24;1:15.
PMID: 17062143 [PubMed]
2:
Refolo LM, Fillit HM.
Abstract
Apolipoprotein E4 as a target for developing new therapeutics for Alzheimer's disease.
J Mol Neurosci. 2004;23(3):151-5. Review.
PMID: 15181243 [PubMed - indexed for MEDLINE]
3:
Fukumoto H, Ingelsson M, Gårevik N, Wahlund LO, Nukina N, Yaguchi Y, Shibata M, Hyman BT, Rebeck GW, Irizarry MC.
Abstract
APOE epsilon 3/ epsilon 4 heterozygotes have an elevated proportion of apolipoprotein E4 in cerebrospinal fluid relative to plasma, independent of Alzheimer's disease diagnosis.
Exp Neurol. 2003 Sep;183(1):249-53.
PMID: 12957508 [PubMed - indexed for MEDLINE]
4:
Manelli AM, Stine WB, Van Eldik LJ, LaDu MJ.
Abstract
ApoE and Abeta1-42 interactions: effects of isoform and conformation on structure and function.
J Mol Neurosci. 2004;23(3):235-46. Review.
PMID: 15181252 [PubMed - indexed for MEDLINE]
5:
Borroni B, Grassi M, Costanzi C, Archetti S, Caimi L, Padovani A.
Abstract
APOE genotype and cholesterol levels in lewy body dementia and Alzheimer disease: investigating genotype-phenotype effect on disease risk.
Am J Geriatr Psychiatry. 2006 Dec;14(12):1022-31. Epub 2006 Sep 6.
PMID: 16956959 [PubMed - indexed for MEDLINE]
6:
Baum L, Chen L, Ng HK, Pang CP.
Abstract
Apolipoprotein E isoforms in Alzheimer's disease pathology and etiology.
Microsc Res Tech. 2000 Aug 15;50(4):278-81. Review.
PMID: 10936880 [PubMed - indexed for MEDLINE]
7:
Sun Y, Wu S, Bu G, Onifade MK, Patel SN, LaDu MJ, Fagan AM, Holtzman DM.
Free Full Text
Glial fibrillary acidic protein-apolipoprotein E (apoE) transgenic mice: astrocyte-specific expression and differing biological effects of astrocyte-secreted apoE3 and apoE4 lipoproteins.
J Neurosci. 1998 May 1;18(9):3261-72.
PMID: 9547235 [PubMed - indexed for MEDLINE]
8:
Lahiri DK, Sambamurti K, Bennett DA.
Abstract
Apolipoprotein gene and its interaction with the environmentally driven risk factors: molecular, genetic and epidemiological studies of Alzheimer's disease.
Neurobiol Aging. 2004 May-Jun;25(5):651-60.
PMID: 15172744 [PubMed - indexed for MEDLINE]
9:
Khachaturian AS, Corcoran CD, Mayer LS, Zandi PP, Breitner JC; Cache County Study Investigators.
Free Full Text
Apolipoprotein E epsilon4 count affects age at onset of Alzheimer disease, but not lifetime susceptibility: The Cache County Study.
Arch Gen Psychiatry. 2004 May;61(5):518-24.
PMID: 15123497 [PubMed - indexed for MEDLINE]
10:
Hsiung GY, Sadovnick AD, Feldman H.
Free in PMC
Apolipoprotein E epsilon4 genotype as a risk factor for cognitive decline and dementia: data from the Canadian Study of Health and Aging.
CMAJ. 2004 Oct 12;171(8):863-7.
PMID: 15477624 [PubMed - indexed for MEDLINE]
11:
Premkumar DR, Cohen DL, Hedera P, Friedland RP, Kalaria RN.
Free in PMC
Apolipoprotein E-epsilon4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology associated with Alzheimer's disease.
Am J Pathol. 1996 Jun;148(6):2083-95.
PMID: 8669492 [PubMed - indexed for MEDLINE]
12:
Saunders AM.
Abstract
Apolipoprotein E and Alzheimer disease: an update on genetic and functional analyses.
J Neuropathol Exp Neurol. 2000 Sep;59(9):751-8. Review.
PMID: 11005255 [PubMed - indexed for MEDLINE]
13:
Devanand DP, Pelton GH, Zamora D, Liu X, Tabert MH, Goodkind M, Scarmeas N, Braun I, Stern Y, Mayeux R.
Free Full Text
Predictive utility of apolipoprotein E genotype for Alzheimer disease in outpatients with mild cognitive impairment.
Arch Neurol. 2005 Jun;62(6):975-80.
PMID: 15956169 [PubMed - indexed for MEDLINE]
14:
Yang DS, Smith JD, Zhou Z, Gandy SE, Martins RN.
Abstract
Characterization of the binding of amyloid-beta peptide to cell culture-derived native apolipoprotein E2, E3, and E4 isoforms and to isoforms from human plasma.
J Neurochem. 1997 Feb;68(2):721-5.
PMID: 9003062 [PubMed - indexed for MEDLINE]
15:
Bizzarro A, Marra C, Acciarri A, Valenza A, Tiziano FD, Brahe C, Masullo C.
Abstract
Apolipoprotein E epsilon4 allele differentiates the clinical response to donepezil in Alzheimer's disease.
Dement Geriatr Cogn Disord. 2005;20(4):254-61. Epub 2005 Aug 9.
PMID: 16103669 [PubMed - indexed for MEDLINE]
16:
Yanagisawa K.
Abstract
[Risk factors for Alzheimer's disease]
Rinsho Shinkeigaku. 2000 Dec;40(12):1225-7. Review. Japanese.
PMID: 11464462 [PubMed - indexed for MEDLINE]
17:
Mulder M, Ravid R, Swaab DF, de Kloet ER, Haasdijk ED, Julk J, van der Boom JJ, Havekes LM.
Abstract
Reduced levels of cholesterol, phospholipids, and fatty acids in cerebrospinal fluid of Alzheimer disease patients are not related to apolipoprotein E4.
Alzheimer Dis Assoc Disord. 1998 Sep;12(3):198-203.
PMID: 9772023 [PubMed - indexed for MEDLINE]
18:
Jordán J, Galindo MF, Miller RJ, Reardon CA, Getz GS, LaDu MJ.
Free Full Text
Isoform-specific effect of apolipoprotein E on cell survival and beta-amyloid-induced toxicity in rat hippocampal pyramidal neuronal cultures.
J Neurosci. 1998 Jan 1;18(1):195-204.
PMID: 9412500 [PubMed - indexed for MEDLINE]
19:
Esler WP, Marshall JR, Stimson ER, Ghilardi JR, Vinters HV, Mantyh PW, Maggio JE.
Abstract
Apolipoprotein E affects amyloid formation but not amyloid growth in vitro: mechanistic implications for apoE4 enhanced amyloid burden and risk for Alzheimer's disease.
Amyloid. 2002 Mar;9(1):1-12.
PMID: 12000192 [PubMed - indexed for MEDLINE]
20:
Raffai RL, Dong LM, Farese RV Jr, Weisgraber KH.
Free in PMC
Introduction of human apolipoprotein E4 "domain interaction" into mouse apolipoprotein E.
Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11587-91. Epub 2001 Sep 11.
PMID: 11553788 [PubMed - indexed for MEDLINE]
Items 1 - 20 of 99
of 5Next