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	1. 857 Accesses	Methodology In vivo measurement of apolipoprotein E from the brain interstitial fluid using microdialysis Jason D Ulrich, Jack M Burchett, Jessica L Restivo, Dorothy R Schuler, Philip B Verghese, Thomas E Mahan, Gary E Landreth, Joseph M Castellano, Hong Jiang, John R Cirrito, David M Holtzman Molecular Neurodegeneration 2013, 8:13 (19 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	2. 787 Accesses	Review α-Synuclein and neuronal cell death Mark R Cookson Molecular Neurodegeneration 2009, 4:9 (4 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	3. 758 Accesses	Review The Alzheimer's disease β-secretase enzyme, BACE1 Sarah L Cole, Robert Vassar Molecular Neurodegeneration 2007, 2:22 (15 November 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	4. 711 Accesses	Methodology Simultaneous and independent detection of C9ORF72 alleles with low and high number of GGGGCC repeats using an optimised protocol of Southern blot hybridisation Vladimir L Buchman, Johnathan Cooper-Knock, Natalie Connor-Robson, Adrian Higginbottom, Janine Kirby, Olga D Razinskaya, Natalia Ninkina, Pamela J Shaw Molecular Neurodegeneration 2013, 8:12 (8 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	5. 667 Accesses	Review Adult hippocampal neurogenesis and its role in Alzheimer's disease Yangling Mu, Fred H Gage Molecular Neurodegeneration 2011, 6:85 (22 December 2011) Abstract \| Full text \| PDF \| PubMed
	6. 656 Accesses	Review Regulated protein aggregation: stress granules and neurodegeneration Benjamin Wolozin Molecular Neurodegeneration 2012, 7:56 (20 November 2012) Abstract \| Full text \| PDF \| PubMed
	7. 623 Accesses	Review HDAC6 as a target for neurodegenerative diseases: what makes it different from the other HDACs? Claudia Simões-Pires, Vincent Zwick, Alessandra Nurisso, Esther Schenker, Pierre-Alain Carrupt, Muriel Cuendet Molecular Neurodegeneration 2013, 8:7 (29 January 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	8. 606 Accesses	Review The amyloid precursor protein: beyond amyloid Hui Zheng, Edward H Koo Molecular Neurodegeneration 2006, 1:5 (3 July 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	9. 562 Accesses	Review Alzheimer's disease: synaptic dysfunction and Aβ Ganesh M Shankar, Dominic M Walsh Molecular Neurodegeneration 2009, 4:48 (23 November 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	10. 550 Accesses	Research article Behavioral characterization of the 6-hydroxidopamine model of Parkinson’s disease and pharmacological rescuing of non-motor deficits Miguel M Carvalho, Filipa L Campos, Bárbara Coimbra, José M Pêgo, Carla Rodrigues, Rui Lima, Ana J Rodrigues, Nuno Sousa, António J Salgado Molecular Neurodegeneration 2013, 8:14 (26 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	11. 501 Accesses	Research article Aggregation and neurotoxicity of recombinant α-synuclein aggregates initiated by dimerization Alireza Roostaee, Simon Beaudoin, Antanas Staskevicius, Xavier Roucou Molecular Neurodegeneration 2013, 8:5 (22 January 2013) Abstract \| Full text \| PDF \| PubMed
	12. 441 Accesses	Review Pathophysiology, treatment, and animal and cellular models of human ischemic stroke Trent M Woodruff, John Thundyil, Sung-Chun Tang, Christopher G Sobey, Stephen M Taylor, Thiruma V Arumugam Molecular Neurodegeneration 2011, 6:11 (25 January 2011) Abstract \| Full text \| PDF \| PubMed
	13. 430 Accesses	Research article Neuron loss in the 5XFAD mouse model of Alzheimer’s disease correlates with intraneuronal Aβ₄₂ accumulation and Caspase-3 activation William A Eimer, Robert Vassar Molecular Neurodegeneration 2013, 8:2 (14 January 2013) Abstract \| Full text \| PDF \| PubMed
	14. 423 Accesses	Research article Exosomal cell-to-cell transmission of alpha synuclein oligomers Karin M Danzer, Lisa R Kranich, Wolfgang P Ruf, Ozge Cagsal-Getkin, Ashley R Winslow, Liya Zhu, Charles R Vanderburg, Pamela J McLean Molecular Neurodegeneration 2012, 7:42 (24 August 2012) Abstract \| Full text \| PDF \| PubMed
	15. 416 Accesses	Research article Identification of BACE2 as an avid ß-amyloid-degrading protease Samer O Abdul-Hay, Tomoko Sahara, Melinda McBride, Dongcheul Kang, Malcolm A Leissring Molecular Neurodegeneration 2012, 7:46 (17 September 2012) Abstract \| Full text \| PDF \| PubMed
	16. 412 Accesses	Review Does neuroinflammation fan the flame in neurodegenerative diseases? Tamy C Frank-Cannon, Laura T Alto, Fiona E McAlpine, Malú G Tansey Molecular Neurodegeneration 2009, 4:47 (16 November 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	17. 409 Accesses	Review Biology and pathophysiology of the amyloid precursor protein Hui Zheng, Edward H Koo Molecular Neurodegeneration 2011, 6:27 (28 April 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	18. 400 Accesses	Review Tau exon 10 alternative splicing and tauopathies Fei Liu, Cheng-Xin Gong Molecular Neurodegeneration 2008, 3:8 (10 July 2008) Abstract \| Full text \| PDF \| PubMed
	19. 390 Accesses	Review The role of tau in neurodegeneration Tania F Gendron, Leonard Petrucelli Molecular Neurodegeneration 2009, 4:13 (11 March 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	20. 392 Accesses	Research article Age-dependent roles of peroxisomes in the hippocampus of a transgenic mouse model of Alzheimer’s disease Francesca Fanelli, Sara Sepe, Marcello D’Amelio, Cinzia Bernardi, Loredana Cristiano, AnnaMaria Cimini, Francesco Cecconi, Maria Ceru', Sandra Moreno Molecular Neurodegeneration 2013, 8:8 (2 February 2013) Abstract \| Full text \| PDF \| PubMed
	21. 388 Accesses	Review Microglia in the aging brain: relevance to neurodegeneration Xiao-Guang Luo, Jian-Qing Ding, Sheng-Di Chen Molecular Neurodegeneration 2010, 5:12 (24 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	22. 349 Accesses	Review All-you-can-eat: autophagy in neurodegeneration and neuroprotection Philipp A Jaeger, Tony Wyss-Coray Molecular Neurodegeneration 2009, 4:16 (6 April 2009) Abstract \| Full text \| PDF \| PubMed
	23. 345 Accesses	Research article Mitochondrial quality, dynamics and functional capacity in Parkinson’s disease cybrid cell lines selected for Lewy body expression Emily N Cronin-Furman, M Kathleen Borland, Kristen E Bergquist, James P Bennett, Patricia A Trimmer Molecular Neurodegeneration 2013, 8:6 (26 January 2013) Abstract \| Full text \| PDF \| PubMed
	24. 335 Accesses	Research article Role of p73 in Alzheimer disease: lack of association in mouse models or in human cohorts Badri Vardarajan, David Vergote, Fadel Tissir, Mark Logue, Jing Yang, Nathalie Daude, Kunie Ando, Ekaterina Rogaeva, Joseph Lee, Rong Cheng, Jean-Pierre Brion, Mahdi Ghani, Beipei Shi, Clinton T Baldwin, Satyabrata Kar, Richard Mayeux, Paul Fraser, André M Goffinet, Peter St George-Hyslop, Lindsay A Farrer, David Westaway Molecular Neurodegeneration 2013, 8:10 (15 February 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	25. 324 Accesses	Research article Normal cognition in transgenic BRI2-Abeta mice Jungsu Kim, Paramita Chakrabarty, Amanda Hanna, Amelia March, Dennis W Dickson, David R Borchelt, Todd Golde, Christopher Janus Molecular Neurodegeneration 2013, 8:15 (12 May 2013) Abstract \| Provisional PDF \| PubMed
	26. 323 Accesses	Research article Microglial phagocytosis induced by fibrillar β-amyloid is attenuated by oligomeric β-amyloid: implications for Alzheimer's disease Xiao-dong Pan, Yuan-gui Zhu, Nan Lin, Jing Zhang, Qin-yong Ye, Hua-pin Huang, Xiao-chun Chen Molecular Neurodegeneration 2011, 6:45 (30 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	27. 323 Accesses	Review Does a loss of TDP-43 function cause neurodegeneration? Zuo-Shang Xu Molecular Neurodegeneration 2012, 7:27 (14 June 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	28. 318 Accesses	Review Oxidative modifications, mitochondrial dysfunction, and impaired protein degradation in Parkinson's disease: how neurons are lost in the Bermuda triangle Kristen A Malkus, Elpida Tsika, Harry Ischiropoulos Molecular Neurodegeneration 2009, 4:24 (5 June 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	29. 305 Accesses	Review Calcium signaling in neurodegeneration Philippe Marambaud, Ute Dreses-Werringloer, Valérie Vingtdeux Molecular Neurodegeneration 2009, 4:20 (6 May 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	30. 303 Accesses	Research article Downregulation of CREB expression in Alzheimer's brain and in Aβ-treated rat hippocampal neurons Subbiah Pugazhenthi, Maorong Wang, Serena Pham, Chun-I Sze, Christopher B Eckman Molecular Neurodegeneration 2011, 6:60 (19 August 2011) Abstract \| Full text \| PDF \| PubMed
	31. 300 Accesses	Research article Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers Rakez Kayed, Elizabeth Head, Floyd Sarsoza, Tommy Saing, Carl W Cotman, Mihaela Necula, Lawrence Margol, Jessica Wu, Leonid Breydo, Jennifer L Thompson, Suhail Rasool, Tatyana Gurlo, Peter Butler, Charles G Glabe Molecular Neurodegeneration 2007, 2:18 (26 September 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	32. 300 Accesses	Review Heat shock protein 90 in neurodegenerative diseases Wenjie Luo, Weilin Sun, Tony Taldone, Anna Rodina, Gabriela Chiosis Molecular Neurodegeneration 2010, 5:24 (3 June 2010) Abstract \| Full text \| PDF \| PubMed
	33. 298 Accesses	Methodology In vivo functional brain mapping in a conditional mouse model of human tauopathy (tau _p301l) reveals reduced neural activity in memory formation structures Pablo D Perez, Gabrielle Hall, Tetsuya Kimura, Yan Ren, Rachel M Bailey, Jada Lewis, Marcelo Febo, Naruhiko Sahara Molecular Neurodegeneration 2013, 8:9 (4 February 2013) Abstract \| Full text \| PDF \| PubMed
	34. 283 Accesses	Review Alzheimer's disease: synapses gone cold Robert M Koffie, Bradley T Hyman, Tara L Spires-Jones Molecular Neurodegeneration 2011, 6:63 (26 August 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	35. 274 Accesses	Research article Utility of an improved model of amyloid-beta (Aβ_1-42) toxicity in Caenorhabditis elegans for drug screening for Alzheimer’s disease Gawain McColl, Blaine R Roberts, Tara L Pukala, Vijaya B Kenche, Christine M Roberts, Christopher D Link, Timothy M Ryan, Colin L Masters, Kevin J Barnham, Ashley I Bush, Robert A Cherny Molecular Neurodegeneration 2012, 7:57 (21 November 2012) Abstract \| Full text \| PDF \| PubMed
	36. 263 Accesses	Research article Kinetics of neurodegeneration based on a risk-related biomarker in animal model of glaucoma Takuya Hayashi, Masamitsu Shimazawa, Hiroshi Watabe, Takayuki Ose, Yuta Inokuchi, Yasushi Ito, Hajime Yamanaka, Shin-ichi Urayama, Yasuyoshi Watanabe, Hideaki Hara, Hirotaka Onoe Molecular Neurodegeneration 2013, 8:4 (18 January 2013) Abstract \| Full text \| PDF \| PubMed
	37. 258 Accesses	Research article Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent and retromer-mediated Sandra I Vieira, Sandra Rebelo, Hermann Esselmann, Jens Wiltfang, James Lah, Rachel Lane, Scott A Small, Sam Gandy, Edgar F da Cruz e Silva, Odete AB da Cruz e Silva Molecular Neurodegeneration 2010, 5:40 (11 October 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	38. 258 Accesses	Research article 6-OHDA generated ROS induces DNA damage and p53- and PUMA-dependent cell death Alison I Bernstein, Sean P Garrison, Gerard P Zambetti, Karen L O'Malley Molecular Neurodegeneration 2011, 6:2 (6 January 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	39. 254 Accesses	Reviewer acknowledgement Reviewer acknowledgement Guojun Bu, Huaxi Xu Molecular Neurodegeneration 2013, 8:11 (2 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	40. 241 Accesses	Lecture presentation Stringently regulated p23 expression is critical for coordinated movement in mice: implications for Alzheimer’s disease Ping Gong, Jelita Roseman, Kulandaivelu S Vetrivel, Vytautas P Bindokas, Lois A Zitzow, Satyabrata Kar, Angèle T Parent, Gopal Thinakaran Molecular Neurodegeneration 2012, 7(Suppl 1):L2 (7 February 2012) Full text \| PDF \| PubMed
	41. 238 Accesses	Research article Involvement of formyl peptide receptors in receptor for advanced glycation end products (RAGE) - and amyloid beta 1-42-induced signal transduction in glial cells Alexander Slowik, Julika Merres, Anne Elfgen, Sandra Jansen, Fabian Mohr, Christoph J Wruck, Thomas Pufe, Lars-Ove Brandenburg Molecular Neurodegeneration 2012, 7:55 (20 November 2012) Abstract \| Full text \| PDF \| PubMed
	42. 237 Accesses	Methodology High-efficiency transfection of cultured primary motor neurons to study protein localization, trafficking, and function Claudia Fallini, Gary J Bassell, Wilfried Rossoll Molecular Neurodegeneration 2010, 5:17 (21 April 2010) Abstract \| Full text \| PDF \| PubMed
	43. 232 Accesses	Research article Regulation of mitochondrial permeability transition pore by PINK1 Clement A Gautier, Emilie Giaime, Erica Caballero, Lucía Núñez, Zhiyin Song, David Chan, Carlos Villalobos, Jie Shen Molecular Neurodegeneration 2012, 7:22 (25 May 2012) Abstract \| Full text \| PDF \| PubMed
	44. 233 Accesses	Research article Dopamine and α-synuclein dysfunction in Smad3 null mice Silvia Tapia-González, Rosa M Giráldez-Pérez, M Isabel Cuartero, M José Casarejos, M Ángeles Mena, Xiao-Fan Wang, Amelia Sánchez-Capelo Molecular Neurodegeneration 2011, 6:72 (13 October 2011) Abstract \| Full text \| PDF \| PubMed \| 1 comment
	45. 231 Accesses	Research article Expression of mutant TDP-43 induces neuronal dysfunction in transgenic mice Ya-Fei Xu, Yong-Jie Zhang, Wen-Lang Lin, Xiangkun Cao, Caroline Stetler, Dennis W Dickson, Jada Lewis, Leonard Petrucelli Molecular Neurodegeneration 2011, 6:73 (26 October 2011) Abstract \| Full text \| PDF \| PubMed
	46. 229 Accesses	Research article Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice Cristian A Lasagna-Reeves, Diana L Castillo-Carranza, Urmi Sengupta, Audra L Clos, George R Jackson, Rakez Kayed Molecular Neurodegeneration 2011, 6:39 (6 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	47. 226 Accesses	Research article LRRK2 knockout mice have an intact dopaminergic system but display alterations in exploratory and motor co-ordination behaviors Kelly M Hinkle, Mei Yue, Bahareh Behrouz, Justus C Dächsel, Sarah J Lincoln, Erin E Bowles, Joel E Beevers, Brittany Dugger, Beate Winner, Iryna Prots, Caroline B Kent, Kenya Nishioka, Wen-Lang Lin, Dennis W Dickson, Christopher J Janus, Matthew J Farrer, Heather L Melrose Molecular Neurodegeneration 2012, 7:25 (30 May 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary LRRK2 knockout mice have a normal dopaminergic system and do not develop any pathological features of Parkinsons disease, but they do display altered exploratory and motor co-ordination behaviors, and degeneration in the kidney.
	48. 225 Accesses	Research article Motor neuron apoptosis and neuromuscular junction perturbation are prominent features in a Drosophila model of Fus-mediated ALS Ruohan Xia, Yajuan Liu, Liuqing Yang, Jozsef Gal, Haining Zhu, Jianhang Jia Molecular Neurodegeneration 2012, 7:10 (24 March 2012) Abstract \| Full text \| PDF \| PubMed
	49. 224 Accesses	Research article Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway Youren Tong, Emilie Giaime, Hiroo Yamaguchi, Takaharu Ichimura, Yumin Liu, Huiqing Si, Huaibin Cai, Joseph V Bonventre, Jie Shen Molecular Neurodegeneration 2012, 7:2 (9 January 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	50. 222 Accesses	Research article Widespread aggregation of mutant VAPB associated with ALS does not cause motor neuron degeneration or modulate mutant SOD1 aggregation and toxicity in mice Linghua Qiu, Tao Qiao, Melissa Beers, Weijia Tan, Hongyan Wang, Bin Yang, Zuoshang Xu Molecular Neurodegeneration 2013, 8:1 (3 January 2013) Abstract \| Full text \| PDF \| PubMed