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1.
784 Accesses
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α-Synuclein and neuronal cell death
Mark R Cookson Molecular Neurodegeneration 2009, 4:9 (4 February 2009)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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2.
699 Accesses
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The Alzheimer's disease β-secretase enzyme, BACE1
Sarah L Cole, Robert Vassar Molecular Neurodegeneration 2007, 2:22 (15 November 2007)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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3.
613 Accesses
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The Alzheimer's β-secretase enzyme BACE1 is required for accurate axon guidance of olfactory sensory neurons and normal glomerulus formation in the olfactory bulb
Tharinda W Rajapaksha, William A Eimer, Thomas C Bozza, Robert Vassar Molecular Neurodegeneration 2011, 6:88 (28 December 2011)
Abstract | Full text | PDF | PubMed
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Editor’s summary
BACE1 inhibitor drugs are currently being developed for the treatment of Alzheimer's disease, however findings suggest that BACE1 is required in axon guidance of olfactory sensory neurons, and its inhibition may cause defects.
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4.
532 Accesses
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Rapid glutamate receptor 2 trafficking during retinal degeneration
Yanhua Lin, Bryan W Jones, Aihua Liu, Felix R Vazquez-Chona, J SCOTT Lauritzen, W DREW Ferrell, Robert E Marc Molecular Neurodegeneration 2012, 7:7 (10 February 2012)
Abstract | Provisional PDF
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5.
514 Accesses
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The amyloid precursor protein: beyond amyloid
Hui Zheng, Edward H Koo Molecular Neurodegeneration 2006, 1:5 (3 July 2006)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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6.
512 Accesses
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Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway
Youren Tong, Emilie Giaime, Hiroo Yamaguchi, Takaharu Ichimura, Yumin Liu, Huiqing Si, Huaibin Cai, Joseph V Bonventre, Jie Shen Molecular Neurodegeneration 2012, 7:2 (9 January 2012)
Abstract | Provisional PDF
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7.
500 Accesses
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Spinal cord trauma and the molecular point of no return
Ping K Yip, Andrea Malaspina Molecular Neurodegeneration 2012, 7:6 (8 February 2012)
Abstract | Provisional PDF
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8.
483 Accesses
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Nurr1 regulates Top IIbeta and functions in axon genesis of mesencephalic dopaminergic neurons
Xin Heng, Gang Jin, Xin Zhang, Dehua Yang, Mingzhe Zhu, Shijun Fu, Xuping Li, Weidong Le Molecular Neurodegeneration 2012, 7:4 (2 February 2012)
Abstract | Provisional PDF
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9.
434 Accesses
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Pathophysiology, treatment, and animal and cellular models of human ischemic stroke
Trent M Woodruff, John Thundyil, Sung-Chun Tang, Christopher G Sobey, Stephen M Taylor, Thiruma V Arumugam Molecular Neurodegeneration 2011, 6:11 (25 January 2011)
Abstract | Full text | PDF | PubMed
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10.
398 Accesses
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Adult hippocampal neurogenesis and its role in Alzheimer's disease
Yangling Mu, Fred H Gage Molecular Neurodegeneration 2011, 6:85 (22 December 2011)
Abstract | Full text | PDF | PubMed
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11.
389 Accesses
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All-you-can-eat: autophagy in neurodegeneration and neuroprotection
Philipp A Jaeger, Tony Wyss-Coray Molecular Neurodegeneration 2009, 4:16 (6 April 2009)
Abstract | Full text | PDF | PubMed
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12.
363 Accesses
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Both common variations and rare non-synonymous substitutions and small insertion/deletions in CLU are associated with increased Alzheimer risk
Karolien Bettens, Nathalie Brouwers, Sebastiaan Engelborghs, Jean-Charles Lambert, Ekaterina Rogaeva, Rik Vandenberghe, Nathalie Le Bastard, Florence Pasquier, Steven Vermeulen, Jasper Van Dongen, Maria Mattheijssens, Karin Peeters, Richard Mayeux, Peter St George-Hyslop, Philippe Amouyel, Peter P De Deyn, Kristel Sleegers, Christine Van Broeckhoven Molecular Neurodegeneration 2012, 7:3 (16 January 2012)
Abstract | Provisional PDF
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13.
343 Accesses
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Dopamine and α-synuclein dysfunction in Smad3 null mice
Silvia Tapia-González, Rosa M Giráldez-Pérez, M Isabel Cuartero, M José Casarejos, M Ángeles Mena, Xiao-Fan Wang, Amelia Sánchez-Capelo Molecular Neurodegeneration 2011, 6:72 (13 October 2011)
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14.
305 Accesses
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WldS but not Nmnat1 protects dopaminergic neurites from MPP+ neurotoxicity
Jo Ann V Antenor-Dorsey, Karen L O'Malley Molecular Neurodegeneration 2012, 7:5 (8 February 2012)
Abstract | Provisional PDF
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15.
299 Accesses
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Does neuroinflammation fan the flame in neurodegenerative diseases?
Tamy C Frank-Cannon, Laura T Alto, Fiona E McAlpine, Malú G Tansey Molecular Neurodegeneration 2009, 4:47 (16 November 2009)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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16.
276 Accesses
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Analysis of striatal transcriptome in mice overexpressing human wild-type alpha-synuclein supports synaptic dysfunction and suggests mechanisms of neuroprotection for striatal neurons
Yofre Cabeza-Arvelaiz, Sheila M Fleming, Franziska Richter, Eliezer Masliah, Marie-Francoise Chesselet, Robert H Schiestl Molecular Neurodegeneration 2011, 6:83 (13 December 2011)
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17.
261 Accesses
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Microglial p38alpha MAPK is critical for LPS-induced neuron degeneration through a mechanism involving TNFalpha
Bin Xing, Adam D Bachstetter, Linda J Van Eldik Molecular Neurodegeneration 2011, 6:84 (20 December 2011)
Abstract | Provisional PDF
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18.
256 Accesses
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GSK3 and p53 - is there a link in Alzheimer's disease?
Carole J Proctor, Douglas A Gray Molecular Neurodegeneration 2010, 5:7 (26 January 2010)
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19.
250 Accesses
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Heat shock protein 90 in neurodegenerative diseases
Wenjie Luo, Weilin Sun, Tony Taldone, Anna Rodina, Gabriela Chiosis Molecular Neurodegeneration 2010, 5:24 (3 June 2010)
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20.
242 Accesses
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Adeno-associated virus-mediated brain delivery of 5-lipoxygenase modulates the AD-like phenotype of APP mice
Jin Chu, Phillip F Giannopoulos, Carolina Ceballos-Diaz, Todd E Golde, Domenico Pratico Molecular Neurodegeneration 2012, 7:1 (5 January 2012)
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21.
241 Accesses
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Alzheimer's disease: synaptic dysfunction and Aβ
Ganesh M Shankar, Dominic M Walsh Molecular Neurodegeneration 2009, 4:48 (23 November 2009)
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22.
234 Accesses
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Dietary composition modulates brain mass and solubilizable Aβ levels in a mouse model of aggressive Alzheimer's amyloid pathology
Steve Pedrini, Carlos Thomas, Hannah Brautigam, James Schmeidler, Lap Ho, Paul Fraser, David Westaway, Peter Hyslop, Ralph N Martins, Joseph D Buxbaum, Giulio M Pasinetti, Dara L Dickstein, Patrick R Hof, Michelle E Ehrlich, Sam Gandy Molecular Neurodegeneration 2009, 4:40 (21 October 2009)
Abstract | Full text | PDF | PubMed
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Editor’s summary
The importance of diet in the pathogenesis of Alzheimer’s disease is becoming clear and new data suggests a correlation between dietary derived factors and sensitization of brain neurons favoring neurotoxicity.
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23.
232 Accesses
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The role of tau in neurodegeneration
Tania F Gendron, Leonard Petrucelli Molecular Neurodegeneration 2009, 4:13 (11 March 2009)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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24.
230 Accesses
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Calcium signaling in neurodegeneration
Philippe Marambaud, Ute Dreses-Werringloer, Valérie Vingtdeux Molecular Neurodegeneration 2009, 4:20 (6 May 2009)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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25.
226 Accesses
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Biology and pathophysiology of the amyloid precursor protein
Hui Zheng, Edward H Koo Molecular Neurodegeneration 2011, 6:27 (28 April 2011)
Abstract | Full text | PDF | PubMed
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