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Research article   Open Access

Reciprocal relationship between APP positioning relative to the membrane and PS1 conformation

Kengo Uemura, Katherine C Farner, Navine Nasser-Ghodsi, Phill Jones, Oksana Berezovska Molecular Neurodegeneration 2011, 6:15 (10 February 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Inhibition of RhoA GTPase and the subsequent activation of PTP1B protects cultured hippocampal neurons against amyloid β toxicity

Pedro J Chacon, Rosa Garcia-Mejias, Alfredo Rodriguez-Tebar Molecular Neurodegeneration 2011, 6:14 (4 February 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Protein S blocks the extrinsic apoptotic cascade in tissue plasminogen activator/N-methyl D-aspartate-treated neurons via Tyro3-Akt-FKHRL1 signaling pathway

Huang Guo, Theresa M Barrett, Zhihui Zhong, José A Fernández, John H Griffin, Robert S Freeman, Berislav V Zlokovic Molecular Neurodegeneration 2011, 6:13 (3 February 2011)

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Research article   Open Access

Tyrosine Phosphorylation of Tau by the Src Family Kinases Lck and Fyn

Timothy ME Scales, Pascal Derkinderen, Kit-Yi Leung, Helen L Byers, Malcolm A Ward, Caroline Price, Ian N Bird, Timothy Perera, Stuart Kellie, Ritchie Williamson, Brian H Anderton, C Hugh Reynolds Molecular Neurodegeneration 2011, 6:12 (26 January 2011)

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Review   Open Access Highly Accessed

Pathophysiology, treatment, and animal and cellular models of human ischemic stroke

Trent M Woodruff, John Thundyil, Sung-Chun Tang, Christopher G Sobey, Stephen M Taylor, Thiruma V Arumugam Molecular Neurodegeneration 2011, 6:11 (25 January 2011)

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Research article   Open Access Highly Accessed

Amyloid beta dimers/trimers potently induce cofilin-actin rods that are inhibited by maintaining cofilin-phosphorylation

Richard C Davis, Ian T Marsden, Michael T Maloney, Laurie S Minamide, Marcia Podlisny, Dennis J Selkoe, James R Bamburg Molecular Neurodegeneration 2011, 6:10 (24 January 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

A novel neuron-enriched protein SDIM1 is down regulated in Alzheimer's brains and attenuates cell death induced by DNAJB4 over-expression in neuro-progenitor cells

Joy X Lei, Cristina G Cassone, Christian Luebbert, Qing Liu Molecular Neurodegeneration 2011, 6:9 (21 January 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Glutathione Peroxidase 4 is associated with Neuromelanin in Substantia Nigra and Dystrophic Axons in Putamen of Parkinson's brain

Frederick P Bellinger, Miyoko T Bellinger, Lucia A Seale, Andrea S Takemoto, Arjun V Raman, Takanori Miki, Amy B Manning-Boğ, Marla J Berry, Lon R White, G Ross Molecular Neurodegeneration 2011, 6:8 (21 January 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Preclinical study of dimebon on β-amyloid-mediated neuropathology in Alzheimer's disease

Jun Wang, Mario G Ferruzzi, Merina Varghese, Xianjuan Qian, Alice Cheng, Mathew Xie, Wei Zhao, Lap Ho, Giulio M Pasinetti Molecular Neurodegeneration 2011, 6:7 (19 January 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Review   Open Access Highly Accessed

Leucine-rich repeat kinase 2 and alpha-synuclein: intersecting pathways in the pathogenesis of Parkinson's disease?

Elisa Greggio, Marco Bisaglia, Laura Civiero, Luigi Bubacco Molecular Neurodegeneration 2011, 6:6 (18 January 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

MyD88-adaptor protein acts as a preventive mechanism for memory deficits in a mouse model of Alzheimer's disease

Jean-Philippe Michaud, Karine L Richard, Serge Rivest Molecular Neurodegeneration 2011, 6:5 (14 January 2011)

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Research article   Open Access

Brimonidine prevents axonal and somatic degeneration of retinal ganglion cell neurons

Wendi S Lambert, Lupe Ruiz, Samuel D Crish, Larry A Wheeler, David J Calkins Molecular Neurodegeneration 2011, 6:4 (13 January 2011)

Abstract | Full text | PDF | PubMed | 1 comment

Review   Open Access

Flipping the switches: CD40 and CD45 modulation of microglial activation states in HIV associated dementia (HAD)

Jon Salemi, Demian F Obregon, Anthony Cobb, Spenser Reed, Edin Sadic, Jingji Jin, Francisco Fernandez, Jun Tan, Brian Giunta Molecular Neurodegeneration 2011, 6:3 (11 January 2011)

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Research article   Open Access Highly Accessed

6-OHDA generated ROS induces DNA damage and p53- and PUMA-dependent cell death

Alison I Bernstein, Sean P Garrison, Gerard P Zambetti, Karen L O'Malley Molecular Neurodegeneration 2011, 6:2 (6 January 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Localization of sequence variations in PGC-1α influence their modifying effect in Huntington disease

Hong Van B Che, Silke Metzger, Esteban Portal, Carolin Deyle, Olaf Riess, Huu Nguyen Molecular Neurodegeneration 2011, 6:1 (6 January 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Protein kinase C and rho activated coiled coil protein kinase 2 (ROCK2) modulate Alzheimer's APP metabolism and phosphorylation of the Vps10-domain protein, SorL1

Rachel F Lane, Joshua W Gatson, Scott A Small, Michelle E Ehrlich, Sam Gandy Molecular Neurodegeneration 2010, 5:62 (30 December 2010)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Identification of BACE1 cleavage sites in human voltage-gated sodium channel beta 2 subunit

Manuel T Gersbacher, Doo Kim, Raja Bhattacharyya, Dora M Kovacs Molecular Neurodegeneration 2010, 5:61 (23 December 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

DNA damage and cell cycle events implicate cerebellar dentate nucleus neurons as targets of Alzheimer's disease

Jianmin Chen, Mark L Cohen, Alan J Lerner, Yan Yang, Karl Herrup Molecular Neurodegeneration 2010, 5:60 (20 December 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Neuroprotective effects and mechanism of cognitive-enhancing choline analogs JWB 1-84-1 and JAY 2-22-33 in neuronal culture and Caenorhabditis elegans

Roongpetch Keowkase, Marwa Aboukhatwa, Bao-Ling Adam, J Warren Beach, Alvin V Terry, Jerry J Buccafussco, Yuan Luo Molecular Neurodegeneration 2010, 5:59 (16 December 2010)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Huntingtin cleavage product A forms in neurons and is reduced by gamma-secretase inhibitors

Kimberly B Kegel, Ellen Sapp, Jonathan Alexander, Patrick Reeves, Dorothee Bleckmann, Linsday Sobin, Nicholas Masso, Antonio Valencia, Hyunkyung Jeong, Dimitri Krainc, James Palacino, Daniel Curtis, Rainer Kuhn, Claudia Betschart, Miguel Sena-Esteves, Neil Aronin, Paolo Paganetti, Marian DiFiglia Molecular Neurodegeneration 2010, 5:58 (14 December 2010)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Conformation dependent monoclonal antibodies distinguish different replicating strains or conformers of prefibrillar Aβ oligomers

Rakez Kayed, Isabel Canto, Leonid Breydo, Suhail Rasool, Tamas Lukacsovich, Jessica Wu, Ricardo Albay, Anna Pensalfini, Stephen Yeung, Elizabeth Head, J Lawrence Marsh, Charles Glabe Molecular Neurodegeneration 2010, 5:57 (13 December 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

ER stress response plays an important role in aggregation of α-synuclein

Peizhou Jiang, Ming Gan, Abdul Ebrahim, Wen-Lang Lin, Heather L Melrose, Shu-Hui C Yen Molecular Neurodegeneration 2010, 5:56 (13 December 2010)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

α-synuclein induced synapse damage is enhanced by amyloid-β1-42

Clive Bate, Steve Gentleman, Alun Williams Molecular Neurodegeneration 2010, 5:55 (7 December 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

ADAR2-dependent RNA editing of GluR2 is involved in thiamine deficiency-induced alteration of calcium dynamics

Shuchen Lee, Guang Yang, Yue Yong, Ying Liu, Liyun Zhao, Jing Xu, Xiaomin Zhang, Yanjie Wan, Chun Feng, Zhiqin Fan, Yong Liu, Jia Luo, Zun-Ji Ke Molecular Neurodegeneration 2010, 5:54 (27 November 2010)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Age-related synaptic loss of the medial olivocochlear efferent innervation

Benjamin Fu, Colleen Le Prell, Dwayne Simmons, Debin Lei, Angela Schrader, Amelia B Chen, Jianxin Bao Molecular Neurodegeneration 2010, 5:53 (26 November 2010)

Abstract | Full text | PDF | PubMed

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