Figure 13.

After 28 days of treatment with GSI + Qa, rPrP^Sc levels remain low for an additional 21 days after treatment is ceased. Estimates of rPrP^Sc concentration (n = 3 mice) in the neocortex (A) and thalamus (B) are given. Relative PrP^Sc levels from untreated infected mice at 78, 85, 92 and 99 dpi were estimated by using data from an earlier study [32]. Adapted from Spilman et al. [8].