Figure 3.

PDGF-B/PDGFRβ interactions occur exclusively on perivascular pericytes in the adult 129S1/SvlmJ mouse brain. (a) High magnification representative confocal imaging analysis of PDGF-B/PDGFRβ proximity interaction (green), PDGFRβ immunodetection of perivascular pericytes (red), and lectin-positive brain capillaries (blue) in 6 month old 129S1/SvlmJ control mouse layer III parietal cortex. Side panels, orthogonal views. Colocalization: yellow. Scale bar 10 μm. (b) High magnification representative confocal imaging analysis of PDGF-B/PDGFRβ proximity interaction (green), PDGFRβ immunodetection of perivascular pericytes (red), and lectin-positive brain capillaries (blue) in 6 month old 129S1/SvlmJ control mouse stratum pyramidale of the CA1 hippocampal subfield. Side panels, orthogonal views. Colocalization: yellow. Scale bar 10 μm.