Additional file 1:

List of genes, expressed within dopaminergic neurons of the midbrain, according to ABA. The list of genes identified by the six screens (Chung et al., Barrett et al., Stewart et al., Greene et al., Thuret et al. and Grimm et al.), after eliminating the duplicates and triplicates, which showed expression patterns similar to tyrosine hydroxylase within ventral midbrain.

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Additional file 2:

Number of genes, identified by six screens, aimed at determining the expression profile of mesDA neurons. Total number of genes, as well as the number of transcripts, expressed in SNpc or VTA, detectable by ISH, within the ABA database is shown. Efficiency of each screen in identifying transcripts, which show above-background expression within either or both of the two regions, according to ABA is between 24–38%, while 56% of the genes from combination of all screens show expression.

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Additional file 3:

Compilation of gene symbols, identified by Neuroblast function of ABA. The template genes Foxa2, En1, Th, Vmat2 and Dat, used for neurblast, are expressed and have defined functions in neurotransmitter phenotype or transcriptional regulation of survival and maintenance of dopaminergic neurons. 250 genes were listed as having similar expression patterns to each template. Repetitions are eliminated from the final list.

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Additional file 4:

Comparison of the list of genes from Neuroblast and genome-wide screens. The comparison of the two lists from additional files 1 &2 show that a fraction of the genes from the six screens, considered by this study can be acquired, using the Neuroblast function.

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