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Table 1
C. elegans transgenic models for human neurodegenerative diseases.
Neurodegeneration-associated protein	Transgene expression	Promoter Sequence	References

Huntingtin::polyQ	chemosensory neurons	osm-10	Faber et al [3]
	mechanosensory neurons	mec-3	Parker et al [11]
	muscle	unc-54	Wang et al [19]

DRPLAP::polyQ	muscle	unc-54	Yamanaka et al [18]

GFP::polyQ	muscle	unc-54	Saytal et al [14]
	pan-neuronal	rgef-1	Brignull et al [82]

α-synuclein	pan-neuronal	aex-3	Lakso et al [21]
	dopaminergic neurons	dat-1
	dopaminergic neurons	dat-1	Cao et al [22]
	dopaminergic neurons	dat-1	Kuwahara et al [23]
	pan-neuronal	unc-51	Kuwahara et al [25]

α-synuclein::GFP	muscle	unc-54	Hamamichi et al [26]
α-synuclein::YFP	muscle	unc-54	van Ham et al [27]

β-amyloid peptide	muscle	unc-54	Link [31]
	inducibe muscle	myo-3	Link et al [38]
	inducible pan-neuronal	snb-1	Wu et al [39]

tau	pan-neuronal	aex-3	Kraemer et al [50]
	mechanosensory neurons	mec-7	Miyasaka et al [57]
	pan-neuronal	rgef-1	Brandt et al [58]

SOD1	muscle	myo-3	Oeda et al [60]
	heat shock inducible	hsp-16.2
	pan-neuronal	snb-1	Wang et al [61]

SOD1::YFP	muscle	unc-54	Gidalevitz et al [62]

LRRK2	pan-neuronal	snb-1	Saha et al [63]

mouse prion protein	muscle	unc-54	Park and Li [64]

Teschendorf and Link Molecular Neurodegeneration 2009 4:38 doi:10.1186/1750-1326-4-38

Table 1