Table 1 |
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Differentially expressed miRNAs in the brain of BSE-infected macaques and their relative abundance in the basis pontis region of macaque brain |
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Regulated miRNAs identified by microarray |
relative abundance in macaque brain [% of highest expressed miRNA] |
regulation factor |
|
|
|
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|
microarray |
stem-loop qRT-PCR |
Poly(A)-tailed qRT-PCR |
|
|
|
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|
hsa-miR-26a |
83,4 |
3.0 ** |
1.0 |
|
hsa-miR-30a-5p |
1,2 |
||
|
hsa-miR-30d |
10,6 |
||
|
hsa-miR-103 |
27,1 |
||
|
hsa-miR-106b |
9,0 |
||
|
hsa-miR-107 |
41,3 |
||
|
hsa-miR-124a |
58,4 |
2.2 |
|
|
hsa-miR-125a |
23,6 |
||
|
hsa-miR-128a |
22,8 |
||
|
hsa-miR-132 |
11,3 |
||
|
hsa-miR-143 |
8,2 |
0.5 |
|
|
hsa-miR-145 |
13,9 |
0.6 |
|
|
hsa-miR-181a |
26,3 |
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|
hsa-miR-191 |
13,9 |
||
|
hsa-miR-195 |
4,9 |
||
|
hsa-miR-219 |
1,3 |
||
|
hsa-miR-320 |
6,9 |
||
|
hsa-miR-342-3p |
8,0 |
2.7 *** |
1.13 *** |
|
hsa-miR-361 |
8,7 |
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|
hsa-miR-490 |
3,6 |
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|
hsa-miR-494 |
2,1 |
3.7 *** |
8.1 *** |
|
|
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** student t-test with Welch's correction; p < 0.01, *** student t-test with Welch's correction; p < 0.001 |
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Montag et al. Molecular Neurodegeneration 2009 4:36 doi:10.1186/1750-1326-4-36 |
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