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Autoimmune-induced preferential depletion of myelin-associated glycoprotein (MAG) is genetically regulated in relapsing EAE (B6 × SJL) F1 mice

Dusanka S Skundric1,2 email, Rujuan Dai1 email, Vaagn L Zakarian3 email and Weili Zhou1 email

1Department of Neurology Wayne State University School of Medicine, Detroit, USA

2Department of Immunology and Microbiology, Wayne State University School of Medicine, Detroit, USA

3Department of Computer Science, University of Colorado, Denver, USA

author email corresponding author email

Molecular Neurodegeneration 2008, 3:7doi:10.1186/1750-1326-3-7

Published: 9 June 2008

Additional files

Additional file 1:

Two-color MBP and NF160 specific immunostaining in spinal cord of relapsing H-2b/s mouse. Lack of co-localization between MBP and NF160 immunostaining may be found, as well as areas of co-localized immunostaining.

Format: JPEG Size: 1.7MB Download file

Additional file 2:

Two-color MBP and NF160 specific immunostaining in spinal cord of relapsing H-2b mouse. Similarly to situation observed in H-2b/s mouse, lack of co-localization, as well as areas of co-localized immunostaining may be found in relapsing H-2b mouse. Note that NF160 immunostaining can not be well appreciated in merged image because of the bright MBP staining, although it is apparent when shown separately

Format: JPEG Size: 1.4MB Download file


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