Figure 4.

HC and FC expression changes are highly correlated. Both plots denote the ALR_PSKO-CNT in the HC (X axis) and FC (Y axis). Each blue diamond represents a single, differentially expressed gene probe. Red dashed line denotes linear regression of the dataset. A. PSKO FC samples reported 70 genes differentially expressed form the FC of CNTs. These genes also showed a highly correlated expression pattern in the HC comparison (Pearson r = 0.89, p < 0.001) B. PSKO HC samples reported 53 genes differentially expressed form the HC of CNTs. These genes also showed a highly correlated expression pattern in the FC comparison (Pearson r = 0.67, p < 0.005).