Figure 8.

PAF antagonists protect against Aβ_1–42 induced synapse damage. Cortical neurons were pre-treated with different concentrations of the PAF antagonists Hexa-PAF (solid circle) or CV6209 (hollow circle) for 3 hours prior to the addition of 100 nM Aβ_1–42 for 24 hours. Values shown are the mean synaptophysin content, ± SD, of 9 observations.