Figure 3.

Ginkgolide B protects cortical neurons against Aβ_1–42-induced loss of synaptophysin. Primary cortical neurons were pre-treated for 3 hours with control medium (solid circle) or with 1 μM ginkgolide B (hollow circle) and subsequently incubated for 24 hours with different concentrations of Aβ_1–42 as shown. Each point represents the mean synaptophysin content ± SD from 9 observations.