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Phosphorylation regulates proteasomal-mediated degradation and solubility of TAR DNA binding protein-43 C-terminal fragments
Yong-Jie Zhang, Tania F Gendron, Ya-Fei Xu, Li-Wen Ko, Shu-Hui Yen, Leonard Petrucelli
Molecular Neurodegeneration 2010, 5:33 (30 August 2010)
[Abstract] [Provisional PDF]
Research article
Pericyte-specific expression of PDGF beta receptor in mouse models with normal and deficient PDGF beta receptor signaling
Ethan A Winkler, Robert D Bell, Berislav V Zlokovic
Molecular Neurodegeneration 2010, 5:32 (25 August 2010)
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Research article
BACE1-/- mice exhibit seizure activity that does not correlate with sodium channel level or axonal localization
Brian D. Hitt, Thomas C. Jaramillo, Dane M. Chetkovich, Robert Vassar
Molecular Neurodegeneration 2010, 5:31 (23 August 2010)
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Research article
Prolonged A treatment leads to impairment in the ability of primary cortical neurons to maintain K+ and Ca2+ homeostasis
Lana Shabala, Claire Howells, Adrian K West, Roger S Chung
Molecular Neurodegeneration 2010, 5:30 (13 August 2010)
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Research article
Aberrant ERK 1/2 complex activation and localization in scrapie-infected GT1-1 cells
Alessandro Didonna, Giuseppe Legname
Molecular Neurodegeneration 2010, 5:29 (9 August 2010)
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Research article
No dramatic age-related loss of hair cells and spiral ganglion neurons in Bcl-2 over-expression mice or Bax null mice
Haiyan Shen, Jonathan I Matsui, Debin Lei, Lirong Han, Kevin K Ohlemiller, Jianxin Bao
Molecular Neurodegeneration 2010, 5:28 (16 July 2010)
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Research article
First evidence of overlaps between HIV-Associated Dementia (HAD) and non-viral neurodegenerative diseases: proteomic analysis of the frontal cortex from HIV+ patients with and without dementia
Li Zhou, Eve Diefenbach, Ben Crossett, Sieu L Tran, Thomas Ng, Helen Rizos, Rejane Rua, Bin Wang, Amit Kapur, Kaushal Gandhi, Bruce J Brew, Nitin K Saksena
Molecular Neurodegeneration 2010, 5:27 (24 June 2010)
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Research article
The mTOR kinase inhibitor Everolimus decreases S6 kinase phosphorylation but fails to reduce mutant huntingtin levels in brain and is not neuroprotective in the R6/2 mouse model of Huntington's disease
Jonathan H Fox, Teal Connor, Vanita Chopra, Kate Dorsey, Jibrin A Kama, Dorothee Bleckmann, Claudia Betschart, Daniel Hoyer, Stefan Frentzel, Marian DiFiglia, Paolo Paganetti, Steven M Hersch
Molecular Neurodegeneration 2010, 5:26 (22 June 2010)
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Research article
Solving a 50 year mystery of a missing OPA1 mutation: more insights from the first family diagnosed with autosomal dominant optic atrophy
Nico Fuhrmann, Simone Schimpf, York Kamenisch, Beate Leo-Kottler, Christiane Alexander, Georg Auburger, Eberhart Zrenner, Bernd Wissinger, Marcel V Alavi
Molecular Neurodegeneration 2010, 5:25 (14 June 2010)
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Review
Heat shock protein 90 in neurodegenerative diseases
Wenjie Luo, Weilin Sun, Tony Taldone, Anna Rodina, Gabriela Chiosis
Molecular Neurodegeneration 2010, 5:24 (3 June 2010)
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Short report
Effect of Apolipoprotein E  4 on the association between health behaviors and cognitive function in late midlife
Séverine Sabia, Mika Kivimaki, Meena Kumari, Martin J Shipley, Archana Singh-Manoux
Molecular Neurodegeneration 2010, 5:23 (1 June 2010)
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Research article
Localization of BDNF mRNA with the Huntington's disease protein in rat brain
Bin Ma, Brady P Culver, Gabriele Baj, Enrico Tongiorgi, Moses V Chao, Naoko Tanese
Molecular Neurodegeneration 2010, 5:22 (27 May 2010)
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Research article
ALS spinal neurons show varied and reduced mtDNA gene copy numbers and increased mtDNA gene deletions
Paula M Keeney, James P Bennett Jr
Molecular Neurodegeneration 2010, 5:21 (26 May 2010)
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Research article
The inhibitory effect of pyrroloquinoline quinone on the amyloid formation and cytotoxicity of truncated alpha-synuclein
Jihoon Kim, Ryuichi Harada, Masaki Kobayashi, Natsuki Kobayashi, Koji Sode
Molecular Neurodegeneration 2010, 5:20 (20 May 2010)
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Research article
Endocytic pathways mediating oligomeric A42 neurotoxicity
Chunjiang Yu, Evelyn Nwabuisi-Heath, Kevin Laxton, Mary Jo LaDu
Molecular Neurodegeneration 2010, 5:19 (17 May 2010)
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Research article
Tetrabenazine is neuroprotective in Huntington's disease mice
Hongyu Wang, Xi Chen, Yuemei Li, Tie-Shan Tang, Ilya Bezprozvanny
Molecular Neurodegeneration 2010, 5:18 (26 April 2010)
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Methodology
High-efficiency transfection of cultured primary motor neurons to study protein localization, trafficking, and function
Claudia Fallini, Gary J Bassell, Wilfried Rossoll
Molecular Neurodegeneration 2010, 5:17 (21 April 2010)
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Research article
ApoE mimetic peptide decreases A production in vitro and in vivo
S Sakura Minami, Antoinette Cordova, John R Cirrito, Joseph A Tesoriero, Lenard W Babus, Gary C Davis, Sivanesan Dakshanamurthy, R Scott Turner, Daniel TS Pak, G William Rebeck, Mikell Paige, Hyang-Sook Hoe
Molecular Neurodegeneration 2010, 5:16 (20 April 2010)
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Research article
Soluble amyloid-, effect on cerebral arteriolar regulation and vascular cells
Hans H Dietrich, Chuanxi Xiang, Byung H Han, Gregory J Zipfel, David M Holtzman
Molecular Neurodegeneration 2010, 5:15 (13 April 2010)
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Review
Lysosomal function in macromolecular homeostasis and bioenergetics in Parkinson's disease
Lonnie Schneider, Jianhua Zhang
Molecular Neurodegeneration 2010, 5:14 (13 April 2010)
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