Molecular Neurodegeneration

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Latest articles

Review

Tau exon 10 alternative splicing and tauopathies
Fei Liu, Cheng-Xin Gong
Molecular Neurodegeneration 2008, 3:8 (10 July 2008)
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Research article

Research article

Changes in -secretase activity and specificity caused by the introduction of consensus aspartyl protease active motif in Presenilin 1
Donald B Carter, Edwige Dunn, Adele M Pauley, Denise D McKinley, Timothy J Fleck, Brenda R Ellerbrook, Nancy C Stratman, Xiangdong Zhou, Carol S Himes, Jeffrey S Nye, Alfredo Tomasselli, Riqiang Yan
Molecular Neurodegeneration 2008, 3:6 (12 May 2008)
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Research article

Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein
Celina V Zerbinatti, Joanna M Cordy, Ci-Di Chen, Maria Guillily, Sokreine Suon, William J Ray, Guy R Seabrook, Carmela R Abraham, Benjamin Wolozin
Molecular Neurodegeneration 2008, 3:5 (18 March 2008)
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Research article

Short report

Dispensable role of Drosophila ortholog of LRRK2 kinase activity in survival of dopaminergic neurons
Danling Wang, Beisha Tang, Guohua Zhao, Qian Pan, Kun Xia, Rolf Bodmer, Zhuohua Zhang
Molecular Neurodegeneration 2008, 3:3 (8 February 2008)
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Research article

Research article

Ginkgolides protect against amyloid-₁₄₂-mediated synapse damage in vitro
Clive Bate, Mourad Tayebi, Alun Williams
Molecular Neurodegeneration 2008, 3:1 (7 January 2008)
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Research article

Review

The Alzheimer's disease -secretase enzyme, BACE1
Sarah L Cole, Robert Vassar
Molecular Neurodegeneration 2007, 2:22 (15 November 2007)
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Methodology

Design of a novel quantitative PCR (QPCR)-based protocol for genotyping mice carrying the neuroprotective Wallerian degeneration slow (Wld^s) gene
Thomas M Wishart, Stephen HF MacDonald, Philip E Chen, Michael J Shipston, Michael P Coleman, Thomas H Gillingwater, Richard R Ribchester
Molecular Neurodegeneration 2007, 2:21 (30 October 2007)
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Research article

Expression profiling in APP23 mouse brain: inhibition of A amyloidosis and inflammation in response to LXR agonist treatment
Iliya Lefterov, Angie Bookout, Zhu Wang, Matthias Staufenbiel, David Mangelsdorf, Radosveta Koldamova
Molecular Neurodegeneration 2007, 2:20 (22 October 2007)
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Research article

Dopaminergic regeneration by neurturin-overexpressing c17.2 neural stem cells in a rat model of Parkinson's disease
Wei-Guo Liu, Xi-Jing Wang, Guo-Qiang Lu, Biao Li, Gang Wang, Sheng-Di Chen
Molecular Neurodegeneration 2007, 2:19 (1 October 2007)
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Research article

Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers
Rakez Kayed, Elizabeth Head, Floyd Sarsoza, Tommy Saing, Carl W Cotman, Mihaela Necula, Lawrence Margol, Jessica Wu, Leonid Breydo, Jennifer L Thompson, Suhail Rasool, Tatyana Gurlo, Peter Butler, Charles G Glabe
Molecular Neurodegeneration 2007, 2:18 (26 September 2007)
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Research article

Tramiprosate, a drug of potential interest for the treatment of Alzheimer's disease, promotes an abnormal aggregation of tau
Ismael Santa-Maria, Félix Hernández, Joaquín Del Rio, Francisco J Moreno, Jesús Avila
Molecular Neurodegeneration 2007, 2:17 (6 September 2007)
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Methodology

Research article

An AICD-based functional screen to identify APP metabolism regulators
Can Zhang, Preeti J Khandelwal, Ranjita Chakraborty, Trinna L Cuellar, Srikant Sarangi, Shyam A Patel, Christopher P Cosentino, Michael O'Connor, Jeremy C Lee, Rudolph E Tanzi, Aleister J Saunders
Molecular Neurodegeneration 2007, 2:15 (24 August 2007)
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Research article

ApoER2 expression increases A production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of -secretase activity
Rodrigo A Fuentealba, Maria Ines Barría, Jiyeon Lee, Judy Cam, Claudia Araya, Claudia A Escudero, Nibaldo C Inestrosa, Francisca C Bronfman, Guojun Bu, Maria-Paz Marzolo
Molecular Neurodegeneration 2007, 2:14 (9 July 2007)
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Commentary

Research article

Tau phosphorylation by GSK-3 promotes tangle-like filament morphology
Carolyn A Rankin, Qian Sun, Truman C Gamblin
Molecular Neurodegeneration 2007, 2:12 (28 June 2007)
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